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A Finite-Element Model of the Mechanical Effects of Implantable Microelectrodes in the Cerebral Cortex
Jeyakumar Subbaroyan, David C. Martin, and Daryl R. Kipke
University of Michigan, USA
The objectives of this study were to develop a finite element model of the probe-brain tissue interface and analyze the effect of tethering forces, and stiffness of the probe substrate on the strain induced around the implant site. A 3-d finite element model of the probe-brain tissue microenvironment was developed in Abaqus 6.4. Tethering forces resulted in elevated strains at the tip and at sharp edges of the probe track in the tissue (see figure below). The model results indicate that flexible substrates could reduce tethering induced injury response in chronic implants by reducing the strain at the probe-tissue interface.
J. Subbaroyan, D. C. Martin, and D. R. Kipke, “A finite-element model of the mechanical effects of implantable microelectrodes in the cerebral cortex”, J. Neural Engineering, Vol. 2, Number 5, pp. 103 - 113, December 2005.
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